The compound was tested at doses of 205, 5.0 and 10 mg/kg against acute inflammation and indomethacin at a dose of 7 mg/kg administrated orally. PubMed:Estrogen-like activity of volatile components from Vitex rotundifolia L. PubMed:Evaluation of the estrogenic activity of the constituents in the fruits of Vitex rotundifolia L. for the potential treatment of premenstrual syndrome. The University of Melbourne, Categorizing invasive weeds: The challenge of rating the weeds already in California, The chronicles of the North Carolina State University Arboretum, Newsletter no. leaves, a. This fruit is used as a dietary supplement for conditions such as menopause, infertility, menstrual problems, and a number of other conditions. Vitex rotundifolia L.f. Family Name: Lamiaceae (Labiatae) Synonyms: Vitex trifolia var. Interim Director, Coastal Research and Education Center, Clemson University, Clemson, SC 29632. ), Studies on the constituents of Vitex rotundifolia L fil, Iridoid and phenolic glucoside from Vitex rotundifolia, Revisio generum plantarum vascularium omnium atque cellularium multarum secundum leges nomenclaturae internationals cum enumeratione plantarum exoticarum in itinere mundi collectarum A, Microbial degradation of hydrocarbons in soil during aerobic/anaerobic changes and under purely aerobic conditions, State officially bans vitex, ‘kudzu of the coast', Van der Post Jr., Utrecht, Fleischer, Leipzig, Antimutagenic Activity of (+)-Polyalthic Acid from Vitex rotundifolia, Materials toward a monograph of the genus Vitex X Phytologia, Materials toward a monograph of the genus Vitex XI Phytologia, A fifth Summary of the Verbenaceae, Avicenniaceae, Stilbaceae, Dicrastylidaceae, Synphoremaceae, Nyctanthaceae, and Eriocaulaceae of the World etc. Interpreting Wetland Status. Vitex rotundifolia L. is an important plant species used in traditional Chinese medicine. Use a sterile planting medium and plant seeds at least ¼ inch deep. A prenylated flavonoid, neougonins A (186) was obtained from the Helminthostachys zeylanica, exhibited the inhibitory action on LPS-induced NO production with an IC50 value of 3.32 μM in RAW264.7 cells [220]. Different species of Vitex vary in chem … Vitex negundo and its medicinal value Mol Biol Rep. 2018 Dec;45(6):2925-2934. doi: 10.1007/s11033-018-4421-3. See Appendix A for the complete assessment. Asian J Tradit Med. elicited apoptotic effects against a broad spectrum of leukemic cell lines, especially human lymphoma HUT78 and H9 cells, with IC50 values equal to 9.5 μg/mL and 6 μg/mL, respectively,152 by possible downregulation of c-Myc and therefore transcription.153 In addition, sclareol at a dose of 100 μM induced apoptosis in the human breast adenocarcinoma (MCF-7) cell-line variants MN1 (wild-type p53) and MDD2 (p53 null) independently of p53.154, The labdane diterpene myriadenolide (CS 2.79) from Alomia myriadenia Sch. All the isolated derivatives were assayed for their biological potential to check ability to inhibit COX-1, COX-2 and 5-LOX. Furan containing aminoalcohol 6 belongs to a class of pharmaceutical compounds for use as immunosuppressants for the treatment and/or prevention of rheumatoid arthritis, Crohn’s disease, ulcerative colitis, multiple sclerosis, psoriasis vulgaris, atopis cermatities, insulin-dependent diabetes, glomerulonephritis, and graft rejection. Cutting the stem and painting is done on both the proximal and distal sides of any locations where significant runner rooting has occurred. Vitex rotundifolia (Pohinahina, pōhinahina) Family: Lamiaceae. The fruits of Vitex rotundifolia L. have long been used for the treatment of inflammation of the respiratory tract in East Asia. Similar Images . Vitex Negundo is a medicinal herb. Keay, ... P.W. Vitex rotundifolia is a sprawling shrub that can grow as tall as 1.5 m though it typically ranges from 0.5 to 1 m in height. 2011; 6 2:54–60. Technical Contribution No. Representatives of fluorenone natural products. A tea made from the leaves and stems has been used in the treatment of rheumatism and stomach problems. 9 and 10 displayed anti-HIV-1 activity with therapeutic index values above 100:1.7 Benzo fluorenone skeleton natural products have also been isolated, such as vitrofolal C and D (11 and 12), which were isolated from the subterranean part of Vitex rotundifolia in 2001, and showed antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA).8. Vitex rotundifolia can be propagated either by seed or by cuttings. The medicinal parts used are the dried leaves and fruits, although the red-black berry is used too. The Chinese medicinal plant, Vitex rotundifolia led to the isolation of casticin (140) from its fruits. Man Jing Zi is also known as Vitex Fruit or Fructus Viticis and is the mature fruit of Vitex trifolia or Vitex rotundifolia. From the structural point view, the fluorenone and azafluorenone containing natural products have various substituted groups on aromatic rings that contribute to the diversity of two groups of natural products. The fruits of Vitex rotundifolia have been used as a folk medicine for the treatment of headache, cold, migraine, eye pain, female hormonal disorders, asthma, chronic bronchitis and gastrointestinal infections, such as diarrhea and bacterial dysentery. Qiaoyan Zhang. ha–1. It has been used for medicinal purposes throughout its native range. Medicinal studies have indicated the potential of BV for cancer therapy. Isoxanthohumol (175) and 8-prenylnaringenin (176) displayed good IL-12 and NF-kB inhibition at a concentration of 5.0 μg/mL. Bip. Search for more papers by this author. [Google Scholar] 10. Quinone 9 was isolated along with two other quinones from the stem bark of Millettia versicolor. The extensive presence of flavonoids in our daily regime also played a key role to keep healthy life due to their anti-inflammatory action. Species record last updated on: 20 April 2020. Occas. Vol. Control efforts are presently underway to protect the fragile beach dune ecosystem. Vitex rotundifolia in China: Implications for its Use and Conservation, IPNI (The International Plant Names Index), Aryl naphthalenes norlignans from Vitex rotundifolia, Phenylnaphthalene compounds from the subterranean part of Vitex rotundifolia and their antibacterial activity against methicillin-resistant Staphylococcus aureus, Invasive plants on disturbed Korea sand dunes, International Collation of Traditional and Folk Medicine, Effects of luteolin on the inhibition of proliferation and induction of apoptosis in human myeloid leukaemia cells, Rotundifuran, a labdane type diterpene from Vitex rotundifolia, induces apoptosis in human myeloid leukaemia cells, Polymethoxy flavonoids from Vitex rotundifolia inhibit proliferation by inducing apoptosis in human myeloid leukemia cells, G2-M arrest and antimitotic activity mediated by casticin, a flavonoid isolated from Viticis Fructus (Vitex rotundifolia Linne fil. Compounds 160, 162, 164, 167, and 168 exhibited significant inhibition on COX-2 at a concentration of 20 μM with comparable to reference compound ibuprofen. Although various synthetic strategies towards the fluorenone1c and azafluorenone9g,h were developed, but due to the relatively simple structures, research in this field mainly relies in the biological studies of the isolated natural products. A mature Vitex rotundifolia produces fragrant, blue-purple flowers that are borne in clusters and ultimately yield small purblish-black fruits. All the compounds displayed significant inhibition of LPS-induced NO production in microglial cells with the IC50 valuses of 18.0 (177), 7.0 (178), 19.7 (179) and 6.7 μM (180), respectively [216]. Any regrowth is treated in the same fashion as before. Copyright © 2020 Elsevier B.V. or its licensors or contributors. Description. Landscaping Features . Germination should occur within 3 to 6 months, although, there have been some instances where seeds have germinated earlier. Bernice P, IFAS Assessment of Non-Native Plants in Florida's Natural Area, In SS-AGR-86. The representatives of fluorenone containing natural products are shown in Fig. Various concentrations of casticin ranging from 0.3 to 10 μM used to treat RAW264.7 cells which were treated with LPS induced inflammation. It is a muscle relaxant and pain relieving herb. Imazapyr effectively controlled BV in these studies whether applied either as a cut stem treatment or as a foliar spray. The metabolite 145–147, 151 and 154 exhibited significant inhibitory activity comparable to standard drug used quercetin (IC50 = 4.4 μM) with the IC50 values of 5.7 (145), 5.7 (146), 5.4 (147), 6.0 (151) and 3.4 μM (154), respectively [211]. Medicinal Plants Medicinal plants and their uses (medicinal herbs) Home » Medicinal and Aromatic Plants » Round Leaf Chastetree, Beach Vitex. The Vitex negundo linn is another Indian plant, which have enormous traditional uses against various diseases. ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. URL: https://www.sciencedirect.com/science/article/pii/B9780123983718000027, URL: https://www.sciencedirect.com/science/article/pii/B9780128110799000148, URL: https://www.sciencedirect.com/science/article/pii/B9780080449920003084, URL: https://www.sciencedirect.com/science/article/pii/S0040402016300850, URL: https://www.sciencedirect.com/science/article/pii/S0223523419305628, Methicillin-Resistant Staphylococcus Aureus, Lead Compounds from Medicinal Plants for the Treatment of Cancer, Natural Products as Source of New Antimicrobial Compounds for Skin Infections, The Microbiology of Skin, Soft Tissue, Bone and Joint Infections, Five-membered Rings with One Heteroatom together with their Benzo and other Carbocyclic-fused Derivatives, Recent advances of synthesis of fluorenone and fluorene containing natural products, Human disorders associated with inflammation and the evolving role of natural products to overcome, Navneet Kishore, ... Akhilesh Kumar Verma, in. 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