J.Clin.Psychiatry 2010;71(6):682-688. Am J Med 11-20-1987;83(5A):35-42. Green T., Steingart L., Frisch A., Zarchi O., Weizman A., Gothelf D. The feasibility and safety of S-adenosyl-L-methionine (SAMe) for the treatment of neuropsychiatric symptoms in 22q11.2 deletion syndrome: a double-blind placebo-controlled trial. BMC.Psychiatry 11-11-2004;4:38. View abstract. Coco helps by gathering the crystals in 17th century Imperial China, the 18th century Pacific Ocean, … Hepatobiliary.Pancreat.Dis.Int. View abstract. View abstract. 2006;29(5):687. Anticancer Res 2003;23(6D):5173-5179. View abstract. Meperidine (Demerol) can also increase serotonin in the brain. Manzillo G, Piccinino F, Surrenti C, and et al. S-adenosyl-L-methionine for treatment of depression, osteoarthritis, and liver disease. S-adenosylmethionine treatment of depression: a controlled clinical trial. J Fam Pract 2002;51:425-30. Aust.N.Z.J.Psychiatry 2013;47(1):26-42. Am J Clin Nutr 2002;76:1172S-6S. Trattamento della steatosi epatica pura o associata ad altre epatopatie. Bombardieri G, Milani A, Bernardi L, and et al. 46-50. View abstract. View abstract. Perna AF, Castaldo P, Ingrosso D, et al. Klin Med (Mosk) 2013;91(2):45-48. Knoll Pharmaceuticals. Harv.Rev.Psychiatry 2000;8(2):84-90. Anales de Psiquiatria 1996;12(2):67-71. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. View abstract. Do not take SAMe if you are taking medications for depression. Mantero, M., Pastorino, P., Carolei, A., and Agnoli, A. Thomas C. S., Bottiglieri T., Edeh J., Carney M. W., Reynolds E. H., Toone B. K. The influence of S-adenosylmethionine (SAM) on prolactin in depressed patients. Clin Ther 2009;31(12):2860-2872. View abstract. Berger R, Nowak H. A new medical approach to the treatment of osteoarthritis. G Mal Infett Parassit 1978;30(8):651-662. "ADA Statement on FDA Toothpaste Warning Labels" https://www.ada.org/prof/prac/issues/statements/fluoride.html (Accessed 18 November 2002). View abstract. View abstract. Am J Med 1987;83:72-7. View abstract. 2011;16(1):17-39. Major depression complicating hemodialysis in patients with chronic renal failure: a multicenter, double-blind, controlled clinical trial of S-adenosyl-L-methionine versus placebo. View abstract. Rosenbaum J. F., Fava M., Falk W. E., Pollack M. H., Cohen L. S., Cohen B. M., Zubenko G. S. An open-label pilot study of oral S-adenosyl-L-methionine in major depression: interim results. Altomare E, Vendemiale G Marchesini G Le Grazie C Di Padova C. Increased bioavailability of sulfurated compounds after s-adeno- sylmethionine (SAMe) administration to alcoholics. Roncaglia N, Locatelli A, Bellini P, and et al. View abstract. Curr Ther Res 1983;33(6):1004-1013. Werneke U, Turner T, Priebe S. Complementary medicines in psychiatry: review of effectiveness and safety. J Clin Psychopharmacol 2004;24(6):661-64. Cochrane Database Syst Rev 2006;(2):CD002235. Williams, A. L., Girard, C., Jui, D., Sabina, A., and Katz, D. L. S-adenosylmethionine (SAMe) as treatment for depression: a systematic review. Defective complex I assembly due to C20orf7 mutations as a new cause of Leigh syndrome. Clinical Nutrition 1992;11:303-308. SAMe increases a chemical in the brain called serotonin. [Pharmacological and clinical aspects of S-adenosylmethionine (SAMe) in primary degenerative arthropathy (osteoarthrosis)]. Mato JM, Camara J, Fernandez de Paz J, et al. View abstract. Gastroenterology 1990;99:211-5. Early research shows that SAMe might reduce ADHD symptoms in adults. 2012;92(4):1515-1542. Facts. J Affect Disord 2009;117 Suppl 1:S54-64. View abstract. J Hepatol 1999;30:1081-9. Clin Trials J 1987;24(4):305-310. Clin Exp Rheumatol 1998;16(1):106-107. View abstract. Acta Neurol Scand Suppl 1994;154:7-14. Evid.Rep.Technol.Assess.(Summ.) This is to see how you respond. View abstract. Effects of S-adenosyl-L-methionine (SAMe) in the treatment of Gilbert's syndrome. Impact of altered methylation in cytokine signaling and proteasome function in alcohol and viral-mediated diseases. Gerards, M., Sluiter, W., van den Bosch, B. J., de Wit, L. E., Calis, C. M., Frentzen, M., Akbari, H., Schoonderwoerd, K., Scholte, H. R., Jongbloed, R. J., Hendrickx, A. T., de Coo, I. F., and Smeets, H. J. Report of an open phase IV study with ademetionine (Gumbaral). Some of these medications used for depression include phenelzine (Nardil), tranylcypromine (Parnate), and others. Kharbanda, K. K. Methionine metabolic pathway in alcoholic liver injury. 2012;200(1):99-101. De Berardis D, Marini S, Serroni N, Rapini G, Iasevoli F, Valchera A, Signorelli M, Aguglia E, Perna G, Salone A, Di Iorio G, Martinotti G, Di Giannantonio M. S-Adenosyl-L-Methionine augmentation in patients with stage II treatment-resistant major depressive disorder: an open label, fixed dose, single-blind study. View abstract. A double-blind, placebo-controlled study. View abstract. J Hepatol 1991;13(Suppl 2):S111. Galizia I, Oldani L, Macritchie K, et al. Comparative clinical trial of S-adenosylmethionine versus nabumetone for the treatment of knee osteoarthritis: an 8-week, multicenter, randomized, double-blind, double-dummy, Phase IV study in Korean patients. View abstract. View abstract. Early research shows that taking SAMe along with the drug sulodexide reduces the amount of time needed to recover from a septic infection. S-Adenosyl-L-methionine: its role in the treatment of liver disorders. View abstract. 2011;17(4):26-37. View abstract. Cergnul I, Jones K, Ernst D, and et al. Review of the clinical studies. Rivista di Neurologia 1979;49(6):417-439. Biomedical and social aspects of alcohol and alcoholism. Confronto con placebo [Effects of SAMe on liver function tests in patients with chronic liver disease. Curr.Opin.Clin.Nutr.Metab Care 2013;16(1):89-95. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Trattamento della steatosi epatica pura o associata ad altre epatopatie. Studio in doppio cieco SAMe (capsule) - Aspirina nell'osteoartrosi. Early research shows that taking a daily multivitamin and SAMe by mouth might reduce stomach pain in children with functional abdominal pain. Alcohol 1994;29:597-604. J.Inherit.Metab Dis. Blood infection (sepsis). Psychother Psychosom 1993;59:34-40. A double-blind study. Lo Russo, A., Monaco, M., Pani, A., and et al. J Ital Psicopatol 1999;5(1):1-16. 2001;35(11):1414-1425. Improvement of aggressive behavior and quality of life impairment following S-adenosyl-methionine (SAM-e) augmentation in schizophrenia. Multicenter placebo controlled clinical trial of intravenous and oral S-adenosyl-L-methionine (SAMe) in cholestatic patients with liver disease [abstract]. View abstract. Biochemistry and pharmacology of S-adenosyl-L-methionine and rationale for its use in liver disease. Eur J Clin Pharmacol 1984;27(1):119-121. Sarris, J. J Neurol Neurosurg Psychiatry 1998;65:23-8. Evaluation of S-adenosyl-L-methionine (SAMe) effectiveness on depression. Kufferle, B. and Grunberger, J. View abstract. View abstract. View abstract. Pecoraro V., Bruno M., Giammona R. L'impiego terapeutico della SAMe (s-adenosil-l-metionina) nella epatite virale acuta [Therapy with SAMe (s-adenosyl-l-methionine) in acute viral hepatitis]. Anales de Psiquiatria 1996;12(2):67-71. View abstract. Gazz Med Ital 1982;141(10):557-562. S-adenosylmethionine for the treatment of intrahepatic cholestasis of pregnancy. View abstract. Aggarwal R, Sentz J, Miller MA. Acta Neurol Scand Suppl 1994;154:19-26. Parenteral S-adenosylmethionine compared to placebos in the treatment of alcoholic liver diseases. SAMe increases a chemical in the brain. Am J Psychiatry 1990;147:591-5. View abstract. Psychological distress during puerperium: a novel therapeutic approach using S-adenosylmethionine. S-adenosyl methionine (SAMe) augmentation in major depressive disorder. Curr Ther Res 1985;37(3):580-585. Am J Psychiatry 1984;141:448-50. View abstract. This information may not fit your specific health circumstances. View abstract. Altern Ther Health Med 2013;19(5):61-4. Kadakia KC, Loprinzi CL, Atherton PJ, Fee-Schroeder KC, Sood A, Barton DL. Alternative Medicine Alert, 1999;12:133-5. American Dental Association. Di Pierro F, Settembre R. Preliminary results of a randomized controlled trial carried out with a fixed combination of S-adenosyl-L-methionine and betaine versus amitriptyline in patients with mild depression. S-adenosyl-L-methionine (SAMe)-induced amelioration of intrahepatic cholestasis of pregnancy. View abstract. 4):90-100. Frezza M, Cammareri G, Di Padova C, and et al. Purohit V, Russo D. Role of S-adenosyl-L-methionine in the treatment of alcoholic liver disease: introduction and summary of the symposium. Ravindran AV, Balneaves LG, Faulkner G, et al. Ala J Med Sci 1988;25(3):301-306. A controlled clinico-therapeutic study]. Aguda [ therapeutic action of SAM in comparison to chlorimipramine intrahepatic cholestasis ] of myalgic encephalomyelitis/chronic fatigue syndrome fibromyalgia..., others ), Norregaard J, Lee EY, Koh EM, et.... 1989 ; 19 ( 10 ):1098-1102, Begleiter AF, et al to completely stop the.... 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